The Safety Evaluation Center of Shenyang Research Institute of Chemical Industry was established in 1982 under a cooperative program supported by UNDP and China former Ministry of Chemical Industry, mainly conducted on the safety evaluation of pesticides, drugs and other fine chemicals. Since 1996, the center has been put into operation in accordance with Good Laboratory Practice (GLP) and has established an advanced safety evaluation experiment system, which can simultaneously perform the safety evaluation for pesticides, medicines, and new chemical substances. The Safety Evaluation Center has passed the National Food and Drug Administration GLP inspection in 2003, and then got the accreditation for the testing of new chemicals by the Ministry of Environmental Protection in 2004, the accreditation by the National Metrology Certification and AAALAC in 2006. In 2010, it became one of the first GLP test units approved by the Ministry of Agriculture. In 2012, the Safety Evaluation Center passed the inspection from the Netherlands authority and became OECD GLP accredited, which is the first OECD GLP certified laboratory in China. In 2014, the OECD GLP has covered six areas including toxicity, analysis, clinical chemistry, genetic toxicity, environmental toxicity, and environmental fate.The center has now become a CRO with the extensive field and strong capacity, and it is also titled as National Pesticide Quality Supervision and Inspection Centre and National Shenyang New Drug Safety Evaluation and Research Center.